twerpules 

A person capable of mythical super-natural like powers of annoyance.

A small bodybuilder. AKA: Mr. Puniverse.

To be unfortunate enough to cross paths with Twerpules, is like suffering twelve labors of ignorant energy sucking monotonous tedium.

twerpules by Jinxoroof August 9, 2018

Twerpules 

Anyone that thinks their ability is far greater than their actual capabilities.

Twerpules, the hero and patron saint of internet tough guys and keyboard warriors

Check out Twerpules antagonizing people from behind the safety of the fence.

Twerpules by Jinxoroof August 9, 2018

twerkulence 

Accidentally passing gas while twerking.

Sentence: "Damn Stephanie, what the hell did you eat before you came to the club? That's some badass twerkulence!!!"

twerkulence by Boris, Bon, Kit & Stephulence August 27, 2014

Twerpess 

The female version of twerp, a silly or annoying woman or girl.

I hate her, she’s a twerpess

Twerpess by ladyfzesimp February 21, 2022

tweepulsive 

twee-puls-iv, adjective: Overly precious and cloying, as in the case of certain Zooey Deschanel facial tics.

As published in Vanity Fair

“No Rain” is actually a great song, even though it inspired the iconically tweepulsive Bee Girl video.

tweepulsive by vita64 June 6, 2012

werpie twerpies

Refering to someone who is clearly not having fun.

"He didn't cruise out tonight cuz he was all werpies twerpies."

"Dude, stop being werpie twerpies and just take that shot."

werpie twerpies by WerpieTwerpies May 4, 2010

Twerkulosis 

An affliction of the lower back caused by twerking without a purpose.

She's at the chiropractor trying to get her twerkulosis straightened out. I'm tired of these amateurs twerking without a purpose.

Twerkulosis by Bsacamano September 18, 2013