Twerpess 

The female version of twerp, a silly or annoying woman or girl.

I hate her, she’s a twerpess

Twerpess by ladyfzesimp February 21, 2022

Twerpes 

TTD (Twitter transmitted disease) contracted when you are followed by a Twitter whore.

I just got Twerpes from this Twitter whore who is following 40,000 other people.

Twerpes by SB1 February 18, 2015