The phrase is used to mean “How is this relevant to the conversation?”, especially if a person seems to be actively avoiding the topic being discussed.
A catchphrase for anybody that doesn't have a catchphrase. It could also be used if you want fucked in the ass and called Billy because it's a cheeseburger
Hey EDP445, Fuck Me In The Ass and Call Me Billy, That's a Cheeseburger, SHIT, NOT LIKE THAT EDP!!!