Take-off 

1. The moment when a mind-altering substance begins to act in one's system.

2. The onset of the effect(s) of a mind-altering substance after its inhalation, ingestion or injection.

Dude, you'll definitely take-off before you finish smoking that giant blunt.

Take-off by m-fun December 15, 2019

Take off

An expression of disbelief, like "Get out of town!", although it can also be used as a Canadian variation of "Fuck off!"

"Take off, eh!"

Take off by Bowman June 16, 2002

take off

a Canadian phrase that was made popular in America with the 1982 winter hit "Take Off!" by comedians Bob and Doug MacKensey. Geddy Lee of Rush provides the actual singing between "verses" that are pretty much spoken by the comedians. Bob and Doug would go on to more success with their Christmas hit, the movie "Strange Brew", and more.

Take off! To the Great White North. Take off!

take off by I Saw U2 Live Twice December 27, 2008

Take off

To leave in a hurry without explanation.

To leave in a hurry rudely

To get the @#-@ out!

Sarcastic saying

A person says to you; hey how you doing... But they are not right with you.... You say, TAKE OFF!

Take off by Michellemybell 88 December 27, 2020

take off

a girl that is fast, loose, sexually active with whom ever she pleases, and will "takeoff" her clothes for any man.

originated in Jacksonville FL school system

"Ah man, I think I love dis girl."
"Whats her name, boy?"
"Alicia, dat girl from Kendall Court"
"Naw! Alicia, fat ass, dick lips? Me and my boys ran through her boy. Dat der you got is a damn take off"

take off by Ni$ce February 21, 2007

Take off!  

a Canadian phrase that was made popular in America with the 1982 winter hit "Take Off!" by Canadian comedians Bob and Doug MacKensey. Geddy Lee of Rush provides the actual singing between the "verses" that are pretty much spoken by the comedians. Bob and Doug would go on to more success with their Christmas hit, the movie "Strange Brew", and more.

Take off! To the Great White North. Take off!

Take off! by I Saw U2 Live Twice June 27, 2007

take off

to initiate a fight. to throw the first punch.

if that bitch keeps talking shit you better take off on his ass.

take off by BigBossMike May 12, 2004