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In Glasgow Scotland it stands for "Tan In One." For which is a game that everyone is playing all the time and the rules state that the person who calls TIO must have a drink in their hand and everyone else with a drink must finish it in one go.
T.I.O by Bucket_the_Great May 11, 2016
This is Oost (This is East, Amsterdam East). Originated from the movie "Blood Diamond". Danny Archer and his Superior "Van de Kaap" are talking about TIA; this is Africa.
Lets trash this place properly, "T.I.O. this is East, welcome!".
T.I.O. by ssan January 7, 2009
The Ignoble Order. An online gaming community of real life friends and a bunch of other a**holes who got picked up along the way.
Ohh man, T.I.O. totally ran a train on my mom last night.
T.I.O. by T.I.O. Reaper July 25, 2011

T.I.O.M. 

touch it once <for> me!
Susie -"You know I hate it when guys are all nicey nice and they tell me to 'give myself a hug!'" ...Bob -"O.K., Well then T.I.O.M. baby, later!"
T.I.O.M. by calcactus January 27, 2008

T.I.O.N. 

Two In One Night. (Tee-awn). Having sex or other activities with two different people in the same night, but at different times.
T.I.O.N. by Unda Dawg November 20, 2017

p e r f e c t i o n 

Emily is p e r f e c t i o n .