Splenda Bitch Share definition Flag Someone who is so fake to the point where you don't even know what they're trying to be. Girl 1: Oh my God, is that Becca? Girl 2: Ugh, yeah, she's such a splenda bitch. Girl 1: Agreed! Splenda Bitch by professional hoe December 4, 2015 0 0 Get merch Get the Splenda Bitch mug. Buy Now — $32.95 See more merch