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its pretty much combining sister and bestie together
Sistie! I love you.

That's my sistie, even tho were sisters, she still my bestie.
Sistie by Domexigringa December 9, 2016
Related Words
Sismie simmie simie simier Siskie sasmie Simieon simieya sisfie Sismey
THE FEMALE VERSION OF A "BROSKIE"
A CLOSE FEMALE FRIEND WHO IS LIKE A SISTER TO YOU
Siskie by yergayy June 4, 2009

Guns are for sissies, real men throw knives! 

When you're fighting some bank robbing criminals with your siblings and one of them needs a good ઽταв
Diego: Guns are for sissies, real men throw knives! *throws knives*

Jim, a news reporter: *from outside* I've been in many hostage situations like this, and it can escalate very quickly.
of or relating to the sign of devil
Guy 1:Yo dog look at that bamf sismick
Guy 2 : wtffff hes got 12 foot horns coming out his head
Only THE most kick ass chicka on the entire face of the planet!!!
Simmie is FUCKEN SEXI!!

OmG BeCky..did you see Simmie'z Butt..its like sooO BIG!
simmie by pEaNuT BuTTa February 2, 2008
yo joe pass me a simmie
simmie by pipes November 3, 2019