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To be right off on something means that you're addiction has taken control of the wheel and is what is driving your actions. Someone who is right off on pills will spend all their money and time just trying to get more pills.

It's the point in time when you go from functioning addict to full blown addict. People who are right off usually lose their job, relationships, apartments, car and anything else of value.
Poor Billy. He's right off on the come. You'd hardly recognize him.

There's absolutely no chance I'm hell I'm letting her babysit when she's right off on the shadies. She'd no doubt try to sell my tv or my kid for a fix.
Right Off by Runtz420 December 3, 2025
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right-off 

Someone gives you news that may be absolutely right; perfectly true, but is not good news. (thus should not be celebrated with the standard "right on")
Hey Bro, we have 8 hours of homework due tomorrow morning. Response: for reals? Right-off!
right-off by D October 3, 2003

Right-off!

He drove home really drunk last night. He’s right-off!
Right-off! by Ceifaroey August 28, 2021

right off the bat 

at once, immediately
from the beginning
"Right off the bat, I could tell it was going to be a crazy night"

"Let's get out of here right off the bat"
right off the bat by glammaniac September 8, 2009

right off the rip bro 

Right from the beginning
I just scored another point right off the rip bro. I am King of foos ball.

right off the smack 

Similar to right off the bat, right off the smack refers to the first thing that is necessary, done, or noticed. The modification of this phrase is used to ground the jargon to just getting off the effect of heroin, smack, which impairs cognitive function.
Right off the smack, if I'm gonna live here I'm going to need hot food, a hot shower, and a hot lay.
right off the smack by ViHelena October 15, 2017

right off the hop 

I went to work this morning and Dave was an idiot right off the hop.