When a person does too much acid or shrumes and their systems are messed up even when they are not on the influence of Acid or Shrumes.
by Permafized June 2, 2009
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Permanently-Fried. When you do so much acid you never come down completely and are never the same. Does NOT mean flash-backs, that's different.
by rubicante June 13, 2003
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Get the permafried mug.When you smoke so much weed that you permanently seem high when sober, permanent stoner eyes (closed ish eyes) and permanent stoned behaviour, people may ask you if you're stoned when you're sober if you're permafried
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