A condition causing one to feel a strange mix of emotions (which may include awe, disappointment, giddiness, emptiness, warmth, and most of all depression) after watching James Cameron's Avatar movie. For many it has changed the way they see the world and life in general.

There are several treatments for someone who has the Pandora Effect; go see the movie again and again, watch youtube videos about Neytiri (or anything Avatar-related), and going to Avatar-Forums.com to find further help.
*walking out of Avatar*
<Guy A>: Mannn, I wanna be a Na'vi... with Neytiri...
<Guy B>: I'm sure there's someone like her.
<Guy A>: But I want HER in her blueness.
<Guy B>: Dude chill, its just a movie... Me toO! *sniff*
<Guy A>: *sniff* I know... looks like we have the Pandora Effect...

*goes back for another showing*
by Eytukan January 3, 2010
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The effect that transcends one's curiosity into an overactive drive/need to experience something, regardless of the ending possibilities. It is different from peer pressure since it does not require external forces, but is similar to physiological effects, such as being horny.
A: I think I wanna get a prostate exam, just to see what it's like
B: That's the Pandora's Box Effect, dude. Don't fall for it.

A few days later

A: I got a prostate exam.
B: You look a little different.
A: You think?
by NTRP January 6, 2021
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