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PKU or Phenylketonuria is a rare genetic disorder in which the enzyme phenylalanine hydroxylase that converts phenylalanine (an amino acid in protein) into tyrosine does not work properly or at all. In this case the phenylalanine builds up in the blood stream and becomes toxic to the central nervous system. This can cause nerological complications like a lack of concentration, mood disorders, loss in IQ, memory loss, and sometimes severe mental retardation. There is no cure for PKU but the treatment includes low-protein diets and medical formula that gives you your lacking nutrients. PKU has been tested for at birth in the USA sine 1965.
I have a rare, inherited metabolic disorder called PKU.
PKU by pkugirl July 9, 2011
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#1

Mikey McFag: OMG GUYZ comment my new pics i took of myself in my bathroom with my iphone!

Carolyn: PKU

#2

Douchey Bus Driver: I DON'T BELIEVE IN SECOND CHANCES. SIT DOWN IN YOUR ASSIGNED SEATS.

Carolyn: PKU PKU PKU
PKU by ynamreGJa September 15, 2010
Related Words
PKU pkugcsq Pkunk
To kick another man in the balls, especially when its uncalled for.
"You got Pkunk'ed! Damn man that shit is whack!"
or
"You deserve to get a Pkunk for that dude!"
or
"Can you believe that shit!? She just went the Pkunk!"
Pkunk by Tazmanian May 15, 2007
pkugcsq
pkugcsq by SeijaKijin September 1, 2021

Stinky Bobby

When you find a little guy who is stinky. Usually needs a belly rub.
Hey, that’s Stinky Bobby.
Stinky Bobby by anorlondo June 17, 2026
Word of the Day on July 29, 2026
A trip to a grocery store, convenience store, or gas station for the sole purpose of buying an excessive amount of junk food and sugary drinks, usually with friends. A chud run often happens late at night and ends with everyone involved hating themselves afterwards.
"Hey bro you tryna go on a chud run with me??"
chud run by chad brandson July 24, 2026
Word of the Day on July 28, 2026

flophouse 

Any house/apartment/frat house/trailer/etc. which is used for individuals to crash (sleep, chill, hang out, lurk, etc.) for a period of time. In order to "crash", one must not actually live there (e.g. have their name on the lease, own said flophouse, etc.). Flophouses are typically used by college students, drug addicts, transients, vagrants, or other unsavory characters.

A flophouse may also be the home owned by the parents of a college student, who after being away at college, wishes to live as if he/she is still at college (e.g. staying out all night, returning just to crash at mom and dad's house, then leaving again), rather than conforming to the pre-college rules.
Example #1
Dude: (Talking to someone passed out face first on the floor of his college apartment) Hey man, who the hell are you? What do you think this is, a flophouse??

Bro: Sorry dude, I must have passed out for a minute.

Example #2
Mom: Where have you BEEN for the last three days? You come home just to sleep?? What do you think this is, a flophouse??!!

Son: What's your problem? I'm an adult now!
flophouse by J3553 November 21, 2007
Word of the Day on July 27, 2026