If you do something once too often it means that you have repeated an action which is bad, stupid or dangerous with an unpleasant end result. So you end up looking a complete wanker, in A & E with serious injuries or someone is totally pissed off with you to an extent which is going to be detrimental to your health and wellbeing.
He’s pissed them off once too often, they’re going to put the fucker on crutches.
aka Ruel van Dijk, the sweetest human bean to ever walk this earth. Also quite tall. Looks cute in bucket hats and literally anything else. Can be spotted dancing awkwardly, yet adorably, at any time or place. Or saying, "AreeeeeeeeeEeeeeE YOU REaaaaaaaaaAaAaAaaaaaal", as it is his famous catchphrase.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.