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A purely fictional spice that is described in the book called "Dune" written by Frank Herbert. It supposedly grants the user either a) all-seeing-ungodly-uber-ability-to-navigate-space or ... b) funky trippy delusions
And it also is said to taste like cinnamon somehow....
The emperor needs X amount of spice by tommorow or his sardukkar will pwn your ass in five hours.
melange by J/M/T/M December 5, 2003

Spice Melange 

The spice. I must have it. The Spice Melange.
Spice Melange by Kanye_w December 9, 2019
The melange of foods made a great flavor
melange by me May 13, 2005
A very beautiful young lady. She is very good at volleyball. People treat her terrible but she’s so kind to everyone. She’s also VERY loyal. Everyone should love her!!!
Have You Seen Melangel I want her to be my freind.
melangel by Klobearforlife March 25, 2018
Partying wit friends, usually in the clubs etc.
Can be heard in many hip hop songs.
Oh, I had a great melange yesterday!
melange by Izzie^^ June 9, 2007
Mixture of sperm and shit in the ass.
(also known as satan nectar)
Girl: what would you drink coffe or tea?
Boy: melange.
Girl: my ass still hurts.
melange by s1nerg1 September 21, 2011