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msdfl is short for microsoft didnt f*cking load. It is used as an exclamation of anger such as WTF and OMG. Was created unintentionaly while spaming random jumbles of letters and trying to make acronyms out of them, and was thus used as described above after a mildly long period of laughter.
Gah! msdfl that guy was lagging so bad!
MSDFL by Barcin November 12, 2008
Related Words

Redneck Testicle Mudflap 

Excess layer of droopy fat found hanging below a redneck's package.
Cooter: I can see your Redneck Testicle Mudflap in those new skinny jeans.

Earl: Curse you Cooter!

Michigan mudflap 

While having sex with a woman and she farts on your balls freckling and flapping them like a mudflap
I was banging my girlfriend and she gave me a Michigan mudflap
Michigan mudflap by Johntanamo September 14, 2016

carolina mudflap 

During vaginal intercourse, inserting your testicles into a woman's anus.
I wasn't able to cum, so I gave her a carolina mudflap. That got 'er done double-time.

Mudflation 

Mudflation is the term used to describe inflation in MMOs.

Unlike in a real economy, there is no fixed amount of currency that circulates, but the amount of currency in circulation continuously increases - whenever a player sells an item to an NPC or receives ingame currency as a reward for a quest, this amount is added onto the money already in circulation, whereas in a real economy, this amount would not be conjured from thin air, but taken out of another entities funds.

Mudflation is very undesirable, as it makes gearing up significantly harder for new players.

Popular Anti-Mudflation mechanisms include ingame mail fees, auction house fees, repairs, upgrading or refining fees or consumables.

More recent East-Asian MMORPGs often have a tendency to have too efficient Anti-Mudflation mechanisms, causing players to become "poorer" as they progress in the game.
Bob sells 20 Smelly Livers to NPC Jim.
Bob receives 10 Gold which the game has just created.
Money in circulation: XXXX Gold + 10 Gold -> Mudflation

Bob sells a can of Red Bull to Joe.
Bob receives 2 Dollars, Joe loses 2 Dollars.
Money in circulation: unchanged
Mudflation by vizzla January 21, 2011

Alabama mudflap 

When a woman's inner vaginal lips are SO huge and hang down so low they can actually fold back and rest against the anus, hence giving them a "muddy" appreance.
Vicky dropped her drawers to reveal the nastiest set of Alabama mudflaps I have ever seen!!!! I think I vomited in my mouth a little!
Alabama mudflap by Leonard W. July 16, 2007