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a nickname for Method Man, a member of the Wu-Tang Clan.
"Yo Mef wheres my killa teeth at?"

Dirty Mef (421 the Day After...)
Mef by Jeff Jang October 25, 2006
Related Words
mef Meff Meffa MEFA Mefter mefail mefe Meffed meffin Meffing
They're tweeking on mef.
Mef by Master Turtle July 20, 2017
mef-derived from the insult meffa or indeed mephloid.
Someone of limited inteligence/extreme clumsyness.
or indeed someone whose limited spacial awareness and general geekiness makes them satnd out from the crowd of geeks
mef by FITZNICENTIGHTLY October 14, 2004
that mef's da shit patna
mef by wuutang March 17, 2004
Highly skilled gamer, not to be confused with 'meth' or similars.
"mef u want a game of q3 m8?"
mef by Aaron September 13, 2003
A word of no meaning other to certify you heard what the other person said, it conveys no emotion. Most commonly used on an instant messenger to stop someone bothering you. Can be used in place of swear words in everyday life.
1. Person A: Are you ok? Person B: Mef
2. Person A: Is something wrong? Person B: Mef
3. DVD fails to record a tv program you wanted to see but could catch another time 'mef' said outloud
mef by Candlemoth September 22, 2008