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When you're working on a simple task and someone fucks your brain so hard that you are no longer able to complete that task.
I was working on reimaging this desktop and then Ron came over and hufnagled me. Now I don't know what the fuck to do so I'm just not going to do it at all.
Hufnagled by StrongArmRon November 6, 2018
Related Words

hofnagle 

When one bite's another's ass
"No hofnagling!"
hofnagle by King of the World December 27, 2003

Hoofnagle 

A device on a multi tool to finagle a stone from a horses hoof. A professor at UW
My horse needed the help of a hoofnagle to walk again
Hoofnagle by Rusagesam January 19, 2018