Frenamone Share definition Flag A sea anemone with which one has developed a tentatively cordial relationship. See frenemy. Sarah presented her finger to the bright red sea anemone, which enveloped it appreciatively. She had a new frenamone. Frenamone by njmac57 January 2, 2011 0 0 Get merch Get the Frenamone mug. Buy Now — $32.95 See more merch