Just another way of saying bumble fuck or bfe. It means even more out of the way than regular Bumble Fuck, being as it's East bumble fuck. Said by pretentious college students, usually.
It took me ages to get here because I just parked in East Bumble Fuck.
Short-hand for the word floccinaucinihilipilification, meaning the estimation of something as valueless (encountered mainly as an example of one of the longest words in the English language).