Deprectile dysfunction 

When you're too sad to jerk off, even though nutting would make you feel better

Guy 1: "I think I'm having Deprectile dysfunction"
Guy 2: "you need to see a therapist dude that stuff sucks to have"

Deprectile dysfunction by Epic989 September 2, 2019

directile dysfunction 

A disability that causes those it afflicts to be unable to follow even the most simple instructions.

Bill: Dude, wtf!?! You were supposed to pick me up at the airport yesterday.

Tom: For realz? I thought that was tomorrow. My directile dysfunction must be acting up again.

directile dysfunction by Jtothebizzy January 23, 2010

Directile Dysfunction 

When your navigation system isn't working.

I wanted to go to Taco Bell, but my navigation to me to the post office. It must be having directile dysfunction.

Directile Dysfunction by LemonZest June 19, 2016

[directile disfunction] 

one who has a great deal of trouble of with directions.

isabella: "where's the bubble tea place?"
lily: "2 blocks to the left, then 1 block up, and then 6 blocks east"
priscilla: "fool, it's right across the street!"
isabella: "dannng girl you got yo self a bad case of directile disfunction"

[directile disfunction] by lilllllly December 16, 2008