Suffering from the effects of excessive consumption, typically alcohol; hungover. Rarely used nowadays but has its roots in the 1500's and is sorely in need of a comeback.
I feel absolutely crapulous. Whoever put that Wild Turkey in the beer bong when I wasn't looking is a real asshole.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.