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A.D means Ass Disease like when a female has a big round ass.
damn those senoritas have a case of A.D
A.D by AHDIU December 22, 2007
Related Words
A.D.A.M. • a.d. • a.d.s. • A.D.O • A.D.I.D.A.S. • A duck! • A- Dub • a dog • a dime • a day
Ass Disease

Similar to S.A.D but smaller in stature.

A.D is when a girl has a round ass.

Blacks & Latinas usually fall victim to A.D Syndrome because of genetics but Whites and Asians are sometimes seen with A.D and sometimes S.A.D
guy: hey did you know you have an A.D
girl: whats that?
guy: Ass Disease!
girl: uh what the hell is that?? no i dont
guy: oooo yess you do!
A.D by diewlaylomo December 21, 2007
Person: hey alexa
Alexa: what?
Person: what's nine plus ten?
Alexa: 21
Person: wow you're a A.D
A.D by Djdkxjd November 8, 2020
They know that they are the best smash bros player
Person 1:did you know that alex got clapped my A.D

Person 2:yes and andres got combo on
A.D by AD Ricardo August 23, 2021
"what was the a.d. of the purchase?"

"let's party on the a.d. of my b-day for a change!"
a.d. by kingman November 16, 2003
Slang used by dealers selling very strong anti-depressants.
A-D is short for anti-depressants.
Originated in South-Florida, often sold in bottle-quantities (e.g. full prescription bottles of 25, 50, or 75)
A-D is also used when referring to anti-depressants among peers.
"Yo man you got any A-D's?"
"Yeah I just got refilled last Wednesday"
--OR--
"Hey dude what A-D are you on?"
"HydrOXYzine 75mg, what about you"
"Paroxetine 25mg"
a-d by bathsaltz November 19, 2015
More from Urban Dictionary

briefcake 

"Did you check out the briefcake in courtroom C?"
briefcake by Ben Frey April 6, 2006
Word of the Day on November 3, 2026
Brought to public attention by Bob Woodward and Carl Bernstein in the book on the fall of Richard Nixon, All The President’s Men, ratfucker was Nixon’s term for a political operative who sows chaos among opponents; an agent provocateur. It is thought to have originated among campus political rivalries at USC, and seems to have some usage in the US military.
Along with Nixon’s other ratfuckers, Roger Stone caused fights at otherwise peaceful Democratic Party protests to generate a false narrative that the Democrats were violent and dangerous.
Ratfucker by Ricky Ramjet November 2, 2017
Word of the Day on November 2, 2026
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