Generically known as a worthless asshole. But more precisely, a prick is an incessantly annoying or obnoxious person who escalates their behavior the more they are ignored.
1: (n.) Vulgar slang term for penis.
2: (n.) A worthless fucking asshole; a true-blue total asshaberdasher.
3: (v.) To stick oneself with a pin, needle, lancet, or other small sharp object; usually to the point of bleeding.
Yeah baby, shove your prick in my asshole!
That fucking prick just stole my Skittles!
Part of diabetes testing involves pricking your finger with a lancet to make it bleed.