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A cat-face emoticon. The ='s are whiskers
Girl: Your cute!
Whoever: =^-^=
=^-^= by Freezy June 28, 2003
A cat themed variation on a happy face (usually ^_^). The equal sign indicates whiskers.
Yay, James finally dumped that skanky ho Melissa, now he'll stop being a douche! =^_^=
=^_^= by Lucas April 10, 2005
(n) A Japanese emoticon symbolizing a cat. This icon is called a "neko" for those who are deeply immersed in the Japanese Culture. To use this emoticon, wait for someone to say something that you wish to respond to with a cute smile.

note: this is most commonly used by females. this can be used as an answer to a question or comment, or however else you wish to use an emoticon.
Girl: egads, I have a shit load of homework...

Boy: -virtual hug!!-

Girl: (=^.^=) awwww!!
(=^.^=) by <(o.0;)> December 9, 2008

(=^-ω-^=) 

It is a cute cat kaomoji many people use like an example,
I got a new cat and they are so adorable! Look at his face!

Cat's face: (=^-ω-^=)

AWWWWWWWWWWWWWWWWW CUTE OVERLOAD!!!
(=^-ω-^=) by GalaxyUniqornKitten December 10, 2020
"Meow, baby!"
=^..^=
=^..^= by mikedlt September 9, 2005
A variable of the ^.^ or ^_^ face. Most coming from someone who is trying to cuten up the face by adding whiskers. This gives a cat like effect.
user 1 : Did you see the kitty??
user 2 : w00t.. lookit teh kitty =^.^=
=^.^= by Robin March 31, 2005