(=-=) 

It usually means someones annoyed. Or this face takes after the meme " Challenge Accepted."

Person 1: "I bet you can run as fast as me." Person 2: "Oh really (=-=)"

(=-=) by TheLawlFace September 21, 2013

=.= 

to squint at someone when they have done something wrong or if they are going to do something wrong

Fred: i ate the last piece of cake...

Samuel: =.=

=.= by kdlfn October 7, 2010

=_= 

An annoyed face often used in chat. Similar to -_- but a little more annoyed. More of a squint, or glare.

Person 1: lol you suck!
Person 2: .... =_= shut up

=_= by BaldDumboRat September 9, 2008

=/=

1. ‘is\are\am not equal to’

or

2. ‘is\are\am not the same as’



(See also: <, >, =, ^)

1. Kirbymak239 =/= Kirbymac293

2. the '=/=' denotation, used primarily by GF'rs, =/= the mathmatical sign '&#8800;' which is a non-ASCII-appropiate character and hence why it is not displayed here

=/= by Victor Van Styn August 23, 2005

=_= 

A smiley derived from anime. Use to define exhaustion, or age.

Uhh... I'm tired. =_=

=_= by KamikazeH2OMelon September 25, 2005

=/=

Not equal to.

gs68 =/= gs68

=/= by dj gs68 July 23, 2003

=.= 

An expression used during a chat etc, to express that you are tired...

A - "Man this weekend sure will be fun!!"
B - "Lucky for you...I have heaps of work to do...=.="

=.= by Sukari March 19, 2004