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derpression 

What most teenagers are actually experiencing when they claim they are suffering from depression. Symptoms include whininess, pointless talk of suicide, crying to strangers over the Internet, and a general lack of common sense.
Trisha: Guys, I crashed my car today, and on top of that, my mom STILL won't let me go to prom. I'm depressed. :(

Jim: No, I think you might be suffering from derpression. You should stop being a derp, wipe your tears, and grow up.
derpression by MusicalRocky December 4, 2010
Related Words
derp Derpy Derping derpes Derper Derped Derpin derpression derp-derp Derpa

Derpy Hooves 

A grey pegasus pony and minor character in the cartoon series My Little Pony. She is best known for her clumsiness and cross-eyed gaze. Originally named Ditzy Doo, she quickly became a favorite among bronies. She likes muffins and delivering mail.
Derpy Hooves can count to muffin. She is not a clever pony.
Derpy Hooves by laofmoonster April 17, 2011
A term meaning scared and coughing
"All that derping for nothing!" -CallMeKevin
Derping by Snake142 December 3, 2020
A terminal disease that took its namesake from herpes. Can be contracted as a result of prolonged exposure to / conversation with trolls or even just overly stupid people.
If contracted, stay indoors and contact your GP immediately, but do not - under any circumstances - converse with them for any longer than needed, lest you infect them in turn with Derpes.
Patient (on telephone): derp lol doc i thnk i gotted derpes
Doctor (on telephone): Good Lord. Are you capable of any coherent speech?
Patient: wat is cohurrent
Doctor (infected): herf i dunno lol
Derpes by ItsjH November 17, 2010

Derptitude 

The overwhelming propensity for being a complete and total derp.
Hey, have you seen Zombie's latest post? His level of derptitude is off the fuckin' charts!

Zombie's complete and utter fail at life is directly proportional to his derptitude.
Derptitude by Bigstugots October 27, 2010

Derpocalypse 

When everyone derps about an apocalypse, but nothing happens. See December 21 2012, Y2K, 2010 Black Hole.
Idiot: "Ermahgerd, the world's gonna end!!!!!!!!11!!one!"
Person: "Meh, I bet it's another Derpocalypse."
Derpocalypse by Desmond The Amazing December 21, 2012