A terminal disease that took its namesake from herpes. Can be contracted as a result of prolonged exposure to / conversation with trolls or even just overly stupid people.
If contracted, stay indoors and contact your GP immediately, but do not - under any circumstances - converse with them for any longer than needed, lest you infect them in turn with Derpes.
Patient (on telephone): derp lol doc i thnk i gotted derpes
Doctor (on telephone): Good Lord. Are you capable of any coherent speech?
Patient: wat is cohurrent
Doctor (infected): herf i dunno lol
by ItsjH November 14, 2010
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1. An internetly transmitted disease, known as an I.T.D. Symptoms include:

- Sweaty Fingers
- Uncontrollable desire to say "derp".
- Hunger
- Fatigue
- Cyber Sex Sessions as to propagate the disease.
- Chat sessions as to propagate the I.T.D

How to cure:
No known cure has been found, yet. Derp.
Anonymous: We owned him. Derp.

Anonymouse: We sure did. Lmfao.

Anonymous: Nice name . Derp

Anonymouse: Oh fuck, you have derpes, don't you? Derp.

Anonymouse: FFFFFuuuuuuuuuuu
by www.Derpes.com January 28, 2010
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Dude, I think Marianna has Derpes. She did it with Manuel last night and he's a retard!
by bhumanjib8uh34 May 14, 2010
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The outcome of what happens when a derp gives a person the herps.
"So I went to the gyno today and I found out I have Herpes."
"I bet that derp boyfriend of yours gave it to you, huh?"
"Shit, your right. So I don't have herpes, I have derpes."
by NeonAcidDrop December 3, 2011
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When one is infected with herpes from someone they know has it.
"Man I really fucked up. The doc just told me I have herpes. Must have got it from Sheila."
"Dude you knew she had the herp! You got yourself the derpes"herpes derp STD
by First Will Rice Lady May 28, 2015
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A small dog possessing one or more of the following characteristics: bulgy eyes, squashed face, eyes that look in two or more directions at the same time, wandering lung, or comically vacuous expression. In short, any dog that arouses feelings of pity, revulsion, and the sneaking suspicion that it would have been kinder to have strangled it at birth.

E.g. pugs, Boston terriers, French bulldogs.
For the origin, do a google search for "hurr durr derp derp derp"
Is that a derp-derp or is she just squeezing her dog too hard?
by Boston Terrierist May 11, 2009
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