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Pretty much the coolest city ever. Involves a lot of badass car chases and wondrous food. New York City and Rochester may say that it's a shithole where you're going to get carjacked, but they're only jealous because we have Loganberry and Mighty Taco.
Innocent Bystander - UGH. I have to drive through BUFFALO this week. Goodbye, sweet world!
Buffalonian - You only say that because you've never had a Super Mighty.
Buffalo by hardcore llama January 25, 2011

Buffalo Run 

A hazing ritual, typically on a football team, in which a bottle of sports drink is forcibly inserted into a lesser member's anus.
"John got the buffalo run at the party last night... Gatorade bottle. I've still got bloodstains on my carpet."
"We're going to buffalo run Smith for fucking up the game!!"
"The captain buffalo'd his lineman."
Buffalo Run by T. K. October 15, 2006

Buffalo Chicken 

Chicken that is cooked in a hot sauce to make it taste better. It is usually served with blue cheese dressing and celery. It can also have bones. Probably the best way chicken can be cooked.
Buffalo Chicken by kittykatmeow March 12, 2009
v. A synonym for vomit, typically used in the Orient. The word likely originated from the term yak, however, due to the ubiquity of yaks in some parts of south central Asia, the term buffalo is more appropriate and less confusing.
Anil: "Oh man, I feel gross! I think I'm gonna buffalo!!"
buffalo by YakLeatherPants May 5, 2011

buffalo sex 

Buffalo Sex has nothing to do with Buffalos but rather with Buffulonians--Not those weird animals roaming the Great Planes--but those poor souls stuck in plain Buffalo, a town of little attraction beset by looming, slack boredom.

Buffalo Sex is any number of the mundane activities of the local inhabitants, used to pass the lonely hours of the long, cold winters in lack of more entertaining or meaningful options of which there are but few. Buffalo Sex is any unexciting passtime, as (un)sexy than the city itself.

The term was coined after the pathetic sexual habits of the locals, i.e., brief sessions of masturbatory scratching, ending anticlimatically or a going-through-the-motions coitus.

However, as its currency spread the term acquired more metaphorical meanings which have nothing to do with sex per se. Although coined after the sorry habits of Buffalo locals, Buffalo Sex is a widespread practice with lots of sub-genres and slippery phenomenology; it is therefore, sometimes hard to detect.

Buffalo Sex could be but is not limited to: 1) Mending old socks.2)Zapping on 3AM on a Monday.3)Picking your nose. 4) Commuting to work.5) Commuting from work. 6) Eating a frozen TV dinner, frozen.5)Popping zits.

buffalo sex by AnnaO January 28, 2006

buffalonian 

The word to describe people from Buffalo, NY. All people from Buffalo refer to themselves as Buffalonians, whether or not Buffaloite is the correct definition. If you're not from Buffalo, then you probably don't know that the only correct term is Buffalonian.
Our favorite Buffalonian, Tim Russert, hosts Meet the Press.