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Hit em up 

Probably the best rap song made as a diss. This song written by 2pac was written because 2pac felt that Biggie and his crew knew that 2pac was going to get mugged and shot but they didn't tell him. 2pac throws this diss at Biggie, P. Diddy, Lil kim, and bad boy records in general, and all of Biggies junior mafia crew. This song is know for its liberal use of swear words. 2pac uses the word fuck or other forms of fuck a total of 43 times in this. This song is one of the many things that makes 2pac superior to Biggie and any other rapper ever to walk this earth.
2pac does nothing but hate on east coast rappers in his song hit em up.
Hit em up by 2pacalypse for ever January 5, 2010
Related Words

hit the pedal 

I want you to hit the pedal tonight
hit the pedal by Guy$1000 June 8, 2014

hit the bottle 

To hit the bottle is to drink alcohol to the point of intoxication.
Brother 1: "Do you think Mom's gonna hit the bottle tonight?"

Brother 2: "Does a bear shit in the woods?"
hit the bottle by neutralmilkhotel January 18, 2006
A person acting sensitive, mad, or butt hurt as if something said applied to them (hit home)

Someone who responds defensively to a general statement, meaning they clearly took it personal
Throw it out there, and a hit dog will holler.

Girls that call the Leykis show tend to be hit dogs because they're always poppin' that "not all women are like that!" sh*t when Tom never said "ALL women."

Old defensive a*s hit dog, I wasn't even talkin' about you in particular, wipe ya mouth!

The right wingers were being hit dogs for Sarah Palin when Obama said "lipstick on a pig."
hit dog by Kuahmel January 22, 2009
(verb) cosmetics term: to use up an eyeshadow to the point where the bottom of the container (er, the "pan") starts to show.
I hit pan on my MAC Patina eyeshadow, so I'll probably be buying another one on my next haul.

I don't use this shadow that much -- after a year I still haven't hit pan.
hit pan by murasakitchan December 15, 2011

hit frog bottom 

Used to describe moments where the vagina has acquired a less than desirable smell. Common instances would be while spending extended periods of time sitting at a desk with tight dress pants on. May also be known as "crotch rot".
"whats up girl..how was work?"
"I tell ya, I hit frog bottom sitting in this chair all day. I don't know what is going on with my junk!"
hit frog bottom by mmrr530 June 15, 2009