Strong ass weed, song made popular by Purple Ribbon (who are da shit), and Superman's worst nightmare.
When Superman hears the song Kryptonite, he takes a baseball bat and starts whamming the crap out of the stereo.
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1. the weakness of an otherwise invulnerable or confident person (especially a heroic person), Achilles' heel

2. crystallized, smokeable cocaine
His only kryptonite was his obsession with political opinions.
by The Return of Light Joker April 5, 2010
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A physical and mental state achieved when heavily under the influence of alcoholic substances.
The drunker you get, you become more akin to Superman when he's near Kryptonite. Unable to stand, talk and make sensible decisions.
Man you should have seen Alex at the pub last nite, he was kryptonited.
by topperharley June 16, 2013
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1. The only substance that can harm wordSuperman.
2. (metaphorical) Something you have a strong aversion to.
1. Kryptonite is Lex Luther's only defense.
2. No mayonaise please; that shit is kryptonite to me.
by zachwolff October 20, 2003
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(n.) a form of crystal methamphetamine that turns into a green liquid when melted for the purpose of the inhallation of its vapors.
Man this ice is kryptonite, this shit is crazy.
by clownpenis January 7, 2006
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Anything that's "poison" to you, something that's so horrible you'll always want to stay away from it.
Sandra loves music by Philip Glass, but she can't stand anything by John Adams. She thinks that John Adams' stuff is musical kryptonite.
by pentozali March 3, 2008
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(noun)
1: A green, radioactive metorite, broken from the distant, late planet of Krypton, that cancels out any Kryptonian's superpowers, such as Superman.
2: Something that is a great weakness to a particular person, such as the aforementioned metiorite to Superman, etc.
1: Krypto the Superdog (of the said show): Kryptonite... my one weakness...
2: Galatea (Justice League Unlimited): Boredom is my kryptonite... well, kryptonite is my kryptonite, but you get the idea.
by DanMat6288 July 11, 2005
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