Not sure how this has no definition yet and generally isn't a more common used figure of speech, because it works in multiple ways.
So, basically
1: If you
don't spill anything on the floor, you're not going to have to clean it up
"Can I trust you to
work alone for a
bit?"
"
Yeah bruh, no issues, no tissues"
2: If there's no problems, then you don't need anything to wipe the tears out of your
face"I'
m fine"
"You been crying, no issues no tissues sis"
3:
A way to respond to someone inquiring requests from you that you currently don't have any
"Dude, should I get you anything from
da store?"
"No issues, no tissues homeboy"
4:
When someone expects one of your experiences to have been way more intense than they really were
"Fell down de stairs"
"Ahh shit musta sucked homie"
"Nah brotha, no issues, tissues"
