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Related Words
Usage #1
Debo is a response given after delivering a command. It means, in so many words, "I can't believe you just did what I told you to do, you're my bitch."

Usage #2
Alternatively, it can also be a response by a third party when someone is brown-nosing someone else.

Usage #3
Debo can be used in many different ways as a common insult.

Usage #4
Sometimes, debo can be used as a reaction to an altercation in which one person is drastically insulted.

Origin
The word, sometimes spelled "deebo", originally comes from the 1995 film "Friday", in which Tiny Lister Jr.'s character is named "Deebo". It was adapted into slang usage in early 1997 in the Metro Detroit region, particularly at Orchard Lake St. Mary's Preparatory, where it became something of a catch phrase.
Usage #1
Man 1: "Will you get that basketball for me?"
Man 2 gets basketball
Man 1: "DEBO!"

Man 1: "Shut up, bitch!"
Man 2 shuts up
Man 1: "DEBO!"

Usage #2
Man 1 (to Man 2): "Gee, I love your jacket. You look amazing."
Man 3: "Damn, DEBO that fool!"

Man 1 (to Man 2): "Do you want me to help you with those groceries!?"
Man 3: "Debo! Slap a dee!" ("slap a dee", applied here often in combination with "debo", means to "get that penis out of your mouth"; in other words, "stop brown-nosing").

Usage #3
Man 1: "Shut your face!"
Man 2 (loudly): "SHUT THE FUCK UP!"
Man 1 (sarcastically): "Debo... Like I'd ever listen to you!"

Usage #4
Man 1: "Yo' momma's first good fuck was last night--with me!!"
Man 2: "Shut up!"
Crowd witnessing altercation: "Oh man, that guy just got DEBOED!"
debo by Geoff February 17, 2005
to knock someone, or something, the fuck out, or to just hit it really hard.
1. you just got debo'd.
2. i debo'd that skank last night.
Debo by kevin02 August 7, 2008
"I'm bout ta debo alla dat boi's jewelry."
debo by Jus2ghetto4ya January 3, 2003
Man, I just deboed that game of Monopoly.
(In rock Climbing) I'm going to debo this V9.
debo by Mryoumajesty July 2, 2007
"She smacked you! YOU GOT DEBOED!"
debo by NunyoBiznas March 29, 2003