it a zit that appears around the mouth. Look like a herpie, but is in fact, a zit. The word zit combined with her pie is.....you guess it..... ZERPIE.
Delany: Ah man, I have a zit by my lip!
Ashley: Dang! that sucks!
Inga:....Thats not a zit, its a zerpie.

Delany: Yes, you are correct. I have a zerpie.
by Selacious Williams April 1, 2014
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The disease you contract whilst muff diving a twat waffle.
Bruh, I contracted zerpies from that twat waffle Janice at Carl's party...shit burns.
by zeroblake December 22, 2017
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Derpies given to you by the zombie hoes on Dead Rising by attempting to give you a nasty blowjob in a failed attempt to kill you.
Dat zombie hoe's trying to give you zerpies! Shake her off and smack that bitch!
by brookensteen August 15, 2010
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An undefinable insult. Usually found in general namecalling.
Don't be such a zerpy-terp.
by Raistlin February 8, 2004
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