Mexican's and Mexican's only (Chicano's too) way of saying weed.
Yo ese, I got some yesca, let me roll it up, and just BLAZE!
by Lady Izamar MTY July 30, 2004
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also known as "street" in Panama; tambien conocida como "calle" en Panama
Let's go sell our arts and crafts in la yesca.
Vamos a parchar nuestro artesania en la yesca.
by mellyy May 20, 2008
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Puertorican word referring to sex; woman looking for sex, bicho
Esta noche estoy buscando yesca!!

Quieres yesca? Bebe!
by AreZ January 23, 2018
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