"Hey TJ, do you want to grab some sushi or maybe a sandwich?"
"No thanks, I'm going to Sonic to grab Spagaco meal that has six Spagacos, gigantic tater-wedges, and the 134 oz liquid-lard soda. Did you know they ship them pre-stuffed with Spaghettios and frozen so they can just throw them in the fryer? They're almost as good as the tacos at Jack-in-the-Box."
To be tweaked or showing apparent signs of being on large amounts of methamphetamine or other drugs, beyond all normal definitions of the word tweeked, tweaking or tweaker.
She was so spaghackled she couldn't keep her jawstill.