smfyoyo 

a way of saying goodbye to someone that you are not endeared to. originally was a term used in WW2 (no i was not born then). It translates to:

Sayonara mother fucker... you're on your own!!!

Can picture Arnold or Bruce saying it while holding an Uzi?

the last words to an ex lover if breaking up by SMS.

"see you soon hon...smfyoyo..."

can also be changed to Spam mother fucker... you're on your own!!! if you suspect the possibility of stalking by email.

smfyoyo by LBelleG January 9, 2008

SMYOYO syndrome 

Medical slang for "Sorry Motherfucker, You're On You're Own". Used when someone has been injured so horribly, there is nothing a doctor can do.

The man was hit by a train, then flung onto the interstate, where he was hit by 6 semi trucks before rolling off the bridge into the river below, being bitten by a water snake, and getting creamed by a speed boat. After he was brought to the hospital, he was diagnosed with SMYOYO syndrome.

SMYOYO syndrome by NINJA_CARROT August 9, 2009

slmfyoyo 

So long, mother fucker! You're on your own!

Oh, you don't wanna hear me out? SLMFYOYO!

slmfyoyo by KiwiSplasher April 8, 2015