The reflexive nonsensical irrational escalating expletive declared in real time during the worst possible nonsensical irrational event.
shit Mother TITTY NUTS! were the last words witnesses reported hearing from Larry before he drowned in earlobe Herpes infested lake water that inexplicably spewed from his laptop after missing the income tax e-Filing deadline by just one minute
As used by Kim Catrall's character, Samantha Jones, in an episode of "Sex and the City"; a situation of extreme misfortune or catastrophe, usually regarding relationship problems, wardrobe malfunctions, or unintended pregnancy. Those involved in "shit mother fucker fuck shit situations" often find it hard to explain themselves when the truth comes out and then find it even harder to repair the damage they cause.
Lacey: "You'll never believe what happened to me yesterday"
Sue: "Bryan found out you were cheating on him with his best friend, didn't he?"
Lacey: "Yep, talk about a shit mother fucker fuck shit situation."
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.