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To recklessly interject your opinion into a situation you have no experience with. To offer unqualified opinions. Reckless action.
Folks want to pop-off and have opinions about what they think they would do. Johnny tried to pop-off medical advice to a real doctor.
Pop-off by Dalkore January 22, 2016
to "work it" or "slay", just absolutely DESTROY the game.
*see's Jessica's fire instagram selfie*

*comments "YAS QUEEN POP OFF" furiously*
Pop off by Seventeen thirty eight September 1, 2018
A term that means to go crazy. When you pop off you do really well in a videogame, rant, argument, or school. Its used all the time during casual talk and can hint that they want you to calm down. Popular people use this term loosly and its hard to precisely define it.
Damn Kiera your popping off
pop off on me then oh my god.
Pop Off by TheOGDefiner69 May 14, 2019
telling someone to fight you. in other words, DO SUMTHIN
Bob: Shut up before i punch you in your face
You: What?! U so hard then pop off!
pop off by Ekho June 6, 2005
An alternative for slay, but somehow better.

When someone does something remarkable, you will comment something like:
pop off by realTaylorSwift13 November 18, 2022
(v.) To lose one's cool; become really pissed off. The idiom is in reference to a pressure cap popping off, usually resulting in a nasty burn or imminent explosion. Thus, the person who caused the pop off is about to get told or be destroyed, depending on the nature and severity of the inflammatory incident.
James: Vernie, your little wigga child is uuuuugly.
Vernie: No you di'int, heeeyll no, heyell no, heyell nah, heyell no, you said what, naaah, heyell no, heyell no, heeeyeeeell, no, etc.
{Vernie has popped off at James' comment}
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Boss: Dave, I know you're a family man, but I need you to come in Saturday... aaaaand Sunday, and stay late every night this week.

Dave: That's cool boss, I'm just gonna need your head in a fucking drill press while I go to work on your nuts with some bolt cutters and run an arc torch down your spine after I've nailed your feet to the floor with a remington power driver.

Boss: Okay Dave, no need to pop off now, I'll get Clarence to do it.