The act of eating way to much pizza and reaching a point of regret in which throwing up feels imminent. Pizza cancer is often achieved at a pizza buffet with extra greasy pizza.
Guy 1: What's wrong with Bill he looks like he's about to die?
Guy 2: He's fine he just got pizza cancer at lunch.
Guy 2: He's fine he just got pizza cancer at lunch.
by cap'n hook December 31, 2012
Get the pizza cancermug.