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The word lesb*ss is a slur directed towards the lesbian community. It is a form of the word l*sbo. It derives from the word girlboss (girl - boss), instead changing it to lesb*ss (les - boss). It is a derogatory term and should NOT be used.
She’s a lesboss.
HEY, LESBOSS!”
lesboss by girlbossxoxoxox October 16, 2021
Related Words
This is a district under the government of a prefect (or prefecture) in Greece. It's made up of a number of islands in the Aegean Sea.

According to Greek mythology, the god of the islands was called 'Lesbos.'

An ancient poet called Sappho wrote about love between women about 2700 years ago and that's where we get the term 'lesbian' from.

Apparently, Sappho's poetry was pretty hot stuff and the Christians didn't like it. Little of it remains today thanks to a policy of it being destroyed by those against it.
Greek 1: "Behold! Across the Aegean sail the lovers Clitus Enormos and Vulva Maximus from the islands of Lesbos!"
Greek 2: "I'm hard as a temple pillar already!"
Lesbos by Wizards Sleeve July 15, 2008

island of lesbos 

Woman dominated land where all women have super human strength. Men feel inferior on the island of lesbos.
After a 15 mile run these women are going to surf 30 foot waves and then take it to the street for some good old-fashioned ass kicking. Smart cocktails to follow. Men feel inferior and insecure on the island of lesbos.
island of lesbos by runbucky January 11, 2021
Don't mess with Gertrude, for she is the Lezboss.
lezboss by Dr K. Jordan April 29, 2007

lesbosian 

Rhodesian, Cretan, Lesbosian... it's all good!

We're sleek, we're Greek -- get used to it!
lesbosian by rapmasta April 29, 2004

resident of the isle of lesbos 

Female who prefers the intimate company of other females.
Jimbo: Man, Dykena is pretty hot.
Billy Joe: Don't bother. She's a resident of the isle of lesbos.