To have had sexual relations with someone.
by humpthewind May 29, 2007

To know someone in the biblical sense means that you have had sexual intercourse with him or her. It is a reference to the meaning of "know" in the Bible.
Man 1: What do you mean by "know in the biblical sense"?
Man 2: I've slept with her. We dated last year.
Man 2: I've slept with her. We dated last year.
by A1988 December 12, 2012
