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Get After It 

To do it. To go hard. To go balls deep. To accomplish something. To improve upon a life-skill. To party with the sickest group of skiers or snowboarders this planet has ever seen.
She's checking you out. Get after it.

You're gonna be late for your pap-smear? You better go get after it.

You didn't land that jump? You didn't get after it enough.
Get After It by Spartan Ski Club October 21, 2011
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Get after it 

(v.) 1. To exert a great deal of effort in pursuance of some worthy goal 2. To perform coitus in a manner satisfactory to both (or all) parties involved
"Get after it dude!"

"Sorry man, I can't go to the hookah bar tonight, I've got to get after it with my girlfriend."
Get after it by Dareh Meyod August 12, 2009

get after it 

To aggressively get fucked up. To go big. To consume party drugs and alcohol in an effort to become extremely wasted, yet still fired up enough to stay up late.
get after it by partyboysf April 8, 2007

Get After It 

To bring fury from the sky.
Get after it like it owes you money.
Get After It by fo_85 November 12, 2011

Get after it 

1.The act of finding any slut that wants the dick

2.Do work
"That bitch just eyefucked the shit out of me, time to get after it."
Get after it by Ryan O'Rourke December 9, 2008

Flat get after it 

Thought to have originated in France, this phrase is used when a homosexual male wants to have sex with another male. so, he tells him to get on his back in preparation for sex. Other countries use the phrase to refer to a female elephant in heat.

Let's get after it 

A milquetoast catchphrase for a steroid-jacked Fredo who once had a lame cable-news show with low ratings, but got fired for corruption and grabbing the asses of other men's wives.
Alright, you 16 viewers who are still watching me, Let's get after it!