duff'd 

When something goes horribly wrong, as in when Hillary Duff was given a recording contract.

1) Did you see that guy get hit by that truck? Man, that was duff'd.

2) That girl's face is duff'd.

duff'd by Mirage December 31, 2004

Duff'd 

Duff'd (v) - The act of getting used and or manipulated by an attractive, mentally unstable person of the opposite sex. Unfortunately this includes an abundance of flirting, profound mixed messages, and sexual enuendos that don't actually lead to SEX, merely the illusion that it will. The Duff usually ends by the Duff-er getting back together with their original girl/boyfriend, leaving the duff-ee with a killer case of blue balls/dry-gina.

Man, I thought this relationship was going to go somewhere, but really I was just totally getting Duff'd!

Duff'd by DFaFH April 25, 2006

duff'd 

when ones pancreas explodes (from duff mckagan of guns n' roses)

dude i was wasted last night i fucked like 4 chinese prostetutes then my pancreas duff'd

duff'd by Caflisch22 May 5, 2006

Duff (D.U.F.F.) 

abv. for Designated Ugly Fat Friend; Term men use to describe a fatter, less attractive friend, a woman brings with her to a party or social gathering to make herself look better by comparison. In some cases the more attractive woman will not "put out" for any male, unless one of his friends "takes one for the team" and "hits" the Duff.

C'mon take one for the team and hit that Duff (D.U.F.F.), I'll buy you lunch tomorrow!

Duff (D.U.F.F.) by Dr. Slappy McGee III Esq. March 19, 2006

Duff Duff 

The drums signifying the cliffhanger at the end of Eastenders.

The end of Eastenders.... duff duff....

Duff Duff by rkelly23 January 27, 2010

Duff Delish 

Duff Delish refers to "a good buzz" or a "really good time". Specifically refers to a drinking/going out/drug buzz. "Duff" refers to being under the influence of substances and "delish" means a nice taste. Has become rather popular around Dublin, Ireland recently.

Chris: What was last night like?
Ronan: I was on such a duff delish, best night of my life.

Duff Delish by bigduffer February 24, 2010

Duff Duff 

A Scandinavian drinking game that can be played by two or more players.

Played in a circle the participants hit a beer can against their head twice with considerable impact (hence duff duff) and then pass the same beer can to their left. The next participant does the same and that continues until the can springs a leak.

The person whose head caused the leak then needs to open the can and down it.

The player to the loser's left takes a fresh can and the game continues.

This drinking game should only be played by skilled experts.

Duff Duff is often played at men only events such as but not limited to: camping trips, bucks parties and festivals.

Duff Duff by Gazcap February 15, 2012