To utterly destroy in a physical battle, mental battle, or any other conflict. To "own" someone so completely as to show supreme domination.
"I so destrominated your cat, dude!"

"I just destrominated your toilet."
by Joseph Jaworski July 12, 2005
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I destrominated Travis last night in Beruit.

We are about to go destrominate the buffet at Chopsticks!
by IV Shep May 07, 2007
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To play a perfect game of beer pong. No misses.
Eddie and I totally Destrominated Joe and Mike to lay claim to the best of 09 cup in the early morning of January 1st 2009.
by Daniel K Webb January 15, 2009
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