defo'sho 

two words combined

Defo (definetly)

+

Fo'sho (For Sure)

Edwin - "Hey Barry would you like to come to mine and grow beards whilst smokings some crack"

Barry - "Defo'sho Mofo"

defo'sho by Johnny Tattoo December 23, 2008

Defo' Fo' Sho'! 

Definitely for sure!

Used when normally two or more people agree on the same topic, not to be confused with William Dafoe.

John: Want to go catch a movie?
Sadie: Sure, what are we gonna watch?
Robert: I was thinking about _______?
Sadie: Defo' fo' sho'!

Defo' Fo' Sho'! by GeneralGrim December 11, 2015