bug up your ass Share definition Flag To be angry about something that is trivial or of little importance. Ramzi, why do you still have a bug up your ass about what I said to you last week. I was only joking...get over it already. bug up your ass by Jessica76 November 25, 2007 0 0 Get merch Get the bug up your ass mug. Buy Now — $32.95 See more merch