Top definition
The guiding spirt, the worldly conscience, the reason for your existance. Without the Weese, we could not thrive, but without us, there would be no Weese at all.
Follow the Weese.

Just listen to your Weese. That's what I do.
by mookymook August 23, 2006
Get the mug
Get a Weese mug for your coworker José.
an unimaginably obnoxious, rare, humorous, obsessive, and crazy being
by Anjroo January 07, 2004
Get the mug
Get a weese mug for your cousin Nathalie.
Cool, awesome, good. It is a word describing something great. It is used in the south (Louisiana and Mississippi mostly). The term apparently stemmed from Mr. Weese who, in the 70's was a New Orleans bigshot.
Chris, he was pretty weese this weekend.
by currecp December 21, 2010
Get the mug
Get a Weese mug for your bunkmate Paul.
buy the domain for your foodie blog