A member of a company or office job who is obnoxious or unbearable most of the time with a result of making you want to mix Jack Daniels with Vicoden everyday.
May: Oh dear Lord, why did they hire that women? She doesn't even do anything, when she does she throws tantrums and bitches.
June: Oh I know, she's such a staff infection.
June: Oh I know, she's such a staff infection.
by surrrra May 26, 2007
Harry claims to have gotten a staff infection at the hospital, but I can't see how that could be --- all the workers there are very careful about germs, so it seems unlikely that he would have caught any illnesses from them. Plus he's such an ugly and obnoxious-natured dude that I seriously doubt that any of the female nurses would have wanted to have sex with him.
by QuacksO October 31, 2018