smallpox 

An acute, highly infectious, often fatal disease caused by a poxvirus and characterized by high fever and aches with subsequent widespread eruption of pimples that blister, produce pus, and form pockmarks. Also called variola.

After 9/11, there was concerns terrorists might use smallpox in an attack.

Supposedly the US holds enough vaccine for it's entire population in case there were ever an outbreak.

Don't get smallpox, or else you are screwed.

smallpox by History Channel November 30, 2005

Smallpox 

lmao

"Smallpox lmao"

Smallpox by TrebuchetIsGod March 11, 2021

Smallpox 

1. The sexually transmitted disease you get from having unprotected sex with a midget. 2. The sexually transmitted disease you get from having unprotected sex with a guy with a small penis.

1. She had a bad case of smallpox after she did the short, short man. 2. She had a bad case of smallpox after she did the short, short man.

Smallpox by chickiechickie September 26, 2007

Smallpox blanketing 

When a white person gives off a false compliment to a person of color in order to gain trust/affection or something back.

Blake: You're so pretty
Lisa: Stop smallpox blanketing me! I know you just want head.

Smallpox blanketing by smallpoxblanketvictim October 7, 2018

SmallBox 

a fictional disease that originates amongst the homeless population (specifically the ones that live in boxes).

Every day, millions of homeless men and women contract the disease "Smallbox." in order to cure these helpless people we must force them to get into the box. the only cure is the box itself.

Symptoms include:

Claustrophobia

poor hygiene
"herpegonasiphilaids"
rash on your underarms

we must find a cure

wow Erin's Smallbox is really bad, maybe she should have gotten into the box instead of rip it up and put it on my bed.

SmallBox by Squishy Squishy ear August 27, 2009

Small Pox 

When a hooker with gingivitis bites your small weiner and it gets infected

Shit bro, your mom gave me small pox

Small Pox by MyNameAdumbMaybe October 29, 2018