S.F.U 

a school designed to obliterate the human soul. see also: fog right angles suicide debt

SFU rendered me incapable of smiling.

S.F.U by shambola September 5, 2004

S.f.u 

Shut fuck up

Zache: Din mamma gay
Emin: S.f.u

S.f.u by InteZache January 9, 2020

S.F.U 

Simon Fraser University

I went to the s.f.u. computer summer camp when i was in grade 5

S.F.U by really_hip December 16, 2003

S.F.U 

Short. Fat. Ugly.

Damn Ashley Martin is S.F.U

S.F.U by sum nigga named weezy f baby December 8, 2009

s.f.u. 

six feet under , aka dead

s.f.u. by Anonymous November 5, 2003

I.F.S.F.U. 

An acronym for "I Feel So Fucked Up". Can be used to refer to yourself in a emotionally or mentally draining state.

Texting:
'ngl ifsfu rn'
(I.F.S.F.U. can be combined with R.N., which is an acronym for "Right Now".)

I.F.S.F.U. by bigboigucci900 January 4, 2023

S.T.F.U. 

An abbreviated form of:

Shut The Fuck Up

Often used in the popular internet comic "Little Gamers" and on internet message board and chat rooms across the nation.

The Sims is teh suxorz.
S.T.F.U!!!!11

S.T.F.U. by molly November 15, 2003