Opie 

Common nickname for red headed white males.

He's a redheaded, opie-looking fella

Opie by Opie Wan December 14, 2008

Opie 

A nickname that is typically used by blacks to refer to any white male.
This modern usage of "Opie" is most likely derived from the character Opie Taylor (played by Ron Howard) on "The Andy Griffith Show" who was the hick son of a hick sherriff in a hick town called Mayberry.
Others characters on this show have also spawned modern nicknames (See Gomer Pyle, Goober Pyle, Aunt Bea, Barney Fife).

Yo, check out Opie over there.

Opie by Ken111 December 28, 2005

Opie 

Lieing sack of shit

Opie by Anonymous November 3, 2003

Opie 

Ron fucking Howard when he was 10.

Be careful or Opie will stab you in the back, take your wallet and spend all your money on drugs. Opie was not the good little boy that Mayberry RFD producers led you to believe.

Opie by Donald Cowboy Cerrone October 14, 2017

Opie 

A derogatory term for generic white Americans. Generally reserved for males of the species, it can also be modified to "Hoe-pie" for white women.

"I can't shop at The Gap or Eddie Bauer. Those stores are strictly for the Opies."

Opie by IncogNegro (FC) November 22, 2002

Opie 

Radio nickname of shock jock Greg Hughes, one half (Anthony Cumia is the other)of the hilarious, if rather raunchy, duo Opie and Anthony.

In a recent magazine interview, Opie said he and Anthony may return to the airwaves on either XM or Siriussatellite radio.

Opie by Led Zeppole March 7, 2004

Opie 

singer for lbda that fell off and dubcat fell off.owner of american beauty tattoo parlor.infamous for passing stds and lying through his gums cause hes missing his two front teeth.

Hey Sally,have you been to the clinic since you had dirty sex with opie?

Opie by opiesx December 28, 2005